Initial responses to questionnaires used to assess participants' understanding of informed consent for malaria vaccine trials conducted in the United States and Mali were tallied. Total scores were analyzed by age, sex, literacy (if known), and location. Ninety-two percent (92%) of answers by United States participants and 85% of answers by Malian participants were correct. Questions more likely to be answered incorrectly in Mali related to risk, and to the type of vaccine. For adult participants, independent predictors of higher scores (...) were younger age and female sex in the United States, and male sex in Mali. Scores in the United States were higher than in Mali (P = 0.005). Despite this difference participants at both sites were well informed overall. Although interpretation must be qualified because questionnaires were not intended as research tools and were not standardized among sites, these results do not support concerns about systematic low understanding among research participants in developing versus developed countries. (shrink)

Atualmente, biotecnologias são empregadas na forma de protocolos a fim de sincronizar o crescimento folicular e a ovulação, bem como permitir que vacas atuem como receptoras de embriões visando melhorar o potencial genético do rebanho. O objetivo desse estudo foi avaliar o efeito da utilização de implantes intravaginais de progesterona de 1º, 2º e 3º uso no protocolo de transferência de embriões em tempo fixo (TETF) sobre a taxa de prenhez em receptoras girolandas. O experimento ocorreu em uma fazenda localizada (...) no município de São Sebastião do Maranhão (MG). Foram utilizadas 74 vacas submetidas aos seguintes protocolos: No dia 0 (D0) administrou-se 2 ml de 17β-Estradiol e progesterona e foi colocado o implante intravaginal de progesterona. Estes implantes foram colocados de forma aleatória, sendo de 1° uso (grupo 1; n=15), 2° (grupo 2; n=24) ou 3° (grupo 3; n=35).No D8, os implantes foram retirados e administrou-se 2 ml PGF2α; 1,5 ml de eCG e 1 ml de 17β-Estradiol e progesterona. A inovulação dos embriões in vitroo correu no D (16) para todas as vacas que apresentaram um corpo lúteo. As variáveis qualitativas (prenhe ou não prenhe) foram comparadas em tabelas de contingência e analisadas pelo teste de qui-quadrado a 5% de probabilidade. Neste estudo não houve diferença estatística entre os grupos protocolados em relação ao aproveitamento como receptoras: 1º uso (53,3%), 2º (79,2%) e 3º (68,65). Ademais, observou-se uma taxa de prenhez entre os grupos de 37,5% para o 1º uso, 42,1% para o 2º e 33,3% para o 3º (P>0,05). Dentre as vantagens ao reaproveitamento dos implantes multiusos destaca-se a redução dos custos dos protocolos hormonais, já que a progesterona é o hormônio mais oneroso, desta forma, a maximização do uso reduz o valor final do protocolo sem prejuízos a taxa de prenhez. (shrink)

Open-content communities that focus on co-creation without requirements for entry have to face the issue of institutional trust in contributors. This research investigates the various ways in which these communities manage this issue. It is shown that communities of open-source software—continue to—rely mainly on hierarchy (reserving write-access for higher echelons), which substitutes (the need for) trust. Encyclopedic communities, though, largely avoid this solution. In the particular case of Wikipedia, which is confronted with persistent vandalism, another arrangement has been pioneered instead. (...) Trust (i.e. full write-access) is ‘backgrounded’ by means of a permanent mobilization of Wikipedians to monitor incoming edits. Computational approaches have been developed for the purpose, yielding both sophisticated monitoring tools that are used by human patrollers, and bots that operate autonomously. Measures of reputation are also under investigation within Wikipedia; their incorporation in monitoring efforts, as an indicator of the trustworthiness of editors, is envisaged. These collective monitoring efforts are interpreted as focusing on avoiding possible damage being inflicted on Wikipedian spaces, thereby being allowed to keep the discretionary powers of editing intact for all users. Further, the essential differences between backgrounding and substituting trust are elaborated. Finally it is argued that the Wikipedian monitoring of new edits, especially by its heavy reliance on computational tools, raises a number of moral questions that need to be answered urgently. (shrink)

In order to fight massive vandalism the English- language Wikipedia has developed a system of surveillance which is carried out by humans and bots, supported by various tools. Central to the selection of edits for inspection is the process of using filters or profiles. Can this profiling be justified? On the basis of a careful reading of Frederick Schauer’s books about rules in general (1991) and profiling in particular (2003) I arrive at several conclusions. The effectiveness, efficiency, and risk-aversion of (...) edit selection all greatly increase as a result. The argument for increasing predictability suggests making all details of profiling manifestly public. Also, a wider distribution of the more sophisticated anti-vandalism tools seems indicated. As to the specific dimensions used in profiling, several critical remarks are developed. When patrollers use ‘assisted edit- ing’ tools, severe ‘overuse’ of several features (anonymity, warned before) is a definite possibility, undermining profile efficacy. The easy remedy suggested is to render all of them invisible on the interfaces as displayed to patrollers. Finally, concerning not only assisted editing tools but tools against vandalism generally, it is argued that the anonymity feature is a sensitive category: anons have been in dispute for a long time (while being more prone to vandalism). Targeting them as a special category violates the social contract upon which Wikipedia is based. The feature is therefore a candidate for mandatory ‘underuse’: it should be banned from all anti-vandalism filters and profiling algorithms, and no longer be visible as a special edit trait. (shrink)

English - language Wikipedia is constantly being plagued by vandalistic contributions on a massive scale. In order to fight them its volunteer contributors deploy an array of software tools and autonomous bots. After an analysis of their functioning and the ‘ coactivity ’ in use between humans and bots, this research ‘ discloses ’ the moral issues that emerge from the combined patrolling by humans and bots. Administrators provide the stronger tools only to trusted users, thereby creating a new hierarchical (...) layer. Further, surveillance exhibits several troubling features : questionable profiling practices, the use of the controversial measure of reputation, ‘ oversurveillance ’ where quantity trumps quality, and a prospective loss of the required moral skills whenever bots take over from humans. The most troubling aspect, though, is that Wikipedia has become a Janus - faced institution. One face is the basic platform of MediaWiki software, transparent to all. Its other face is the anti - vandalism system, which, in contrast, is opaque to the average user, in particular as a result of the algorithms and neural networks in use. Finally it is argued that this secrecy impedes a much needed discussion to unfold ; a discussion that should focus on a ‘ rebalancing ’ of the anti - vandalism system and the development of more ethical information practices towards contributors. (shrink)

Can trust evolve on the Internet between virtual strangers? Recently, Pettit answered this question in the negative. Focusing on trust in the sense of ‘dynamic, interactive, and trusting’ reliance on other people, he distinguishes between two forms of trust: primary trust rests on the belief that the other is trustworthy, while the more subtle secondary kind of trust is premised on the belief that the other cherishes one’s esteem, and will, therefore, reply to an act of trust in kind (‘trust-responsiveness’). (...) Based on this theory Pettit argues that trust between virtual strangers is impossible: they lack all evidence about one another, which prevents the imputation of trustworthiness and renders the reliance on trust-responsiveness ridiculous. I argue that this argument is flawed, both empirically and theoretically. In several virtual communities amazing acts of trust between pure virtuals have been observed. I propose that these can be explained as follows. On the one hand, social cues, reputation, reliance on third parties, and participation in (quasi-) institutions allow imputing trustworthiness to varying degrees. On the other, precisely trust-responsiveness is also relied upon, as a necessary supplement to primary trust. In virtual markets, esteem as a fair trader is coveted while it contributes to building up one’s reputation. In task groups, a hyperactive style of action may be adopted which amounts to assuming (not: inferring) trust. Trustors expect that their virtual co-workers will reply in kind while such an approach is to be considered the most appropriate in cyberspace. In non-task groups, finally, members often display intimacies while they are confident someone else ‘out there’ will return them. This is facilitated by the one-to-many, asynchronous mode of communication within mailing lists. (shrink)

The ideas behind open source software are currently applied to the production of encyclopedias. A sample of six English text-based, neutral-point-of-view, online encyclopedias of the kind are identified: h2g2, Wikipedia, Scholarpedia, Encyclopedia of Earth, Citizendium and Knol. How do these projects deal with the problem of trusting their participants to behave as competent and loyal encyclopedists? Editorial policies for soliciting and processing content are shown to range from high discretion to low discretion; that is, from granting unlimited trust to limited (...) trust. Their conceptions of the proper role for experts are also explored and it is argued that to a great extent they determine editorial policies. Subsequently, internal discussions about quality guarantee at Wikipedia are rendered. All indications are that review and ?super-review? of new edits will become policy, to be performed by Wikipedians with a better reputation. Finally, while for encyclopedias the issue of organizational trust largely coincides with epistemological trust, a link is made with theories about the acceptance of testimony. It is argued that both non-reductionist views (the ?acceptance principle? and the ?assurance view?) and reductionist ones (an appeal to background conditions, and a?newly defined??expertise view?) have been implemented in editorial strategies over the past decade. (shrink)

Many virtual communities that rely on user-generated content (such as social news sites, citizen journals, and encyclopedias in particular) offer unrestricted and immediate ‘write access’ to every contributor. It is argued that these communities do not just assume that the trust granted by that policy is well-placed; they have developed extensive mechanisms that underpin the trust involved (‘backgrounding’). These target contributors (stipulating legal terms of use and developing etiquette, both underscored by sanctions) as well as the contents contributed by them (...) (patrolling for illegal and/or vandalist content, variously performed by humans and bots; voting schemes). Backgrounding trust is argued to be important since it facilitates the avoidance of bureaucratic measures that may easily cause unrest among community members and chase them away. (shrink)

The traditional use of conventional media by businesses for audience targeting has shifted with the rise of influencer marketing, notably on platforms like TikTok, posing challenges in content adaptation and technological adaptation. Albert Bandura's Social Cognitive Theory examines factors shaping purchasing behavior, particularly relevant for young professionals. A quantitative correlational study focused on young professionals engaging with TikTok and influenced by Filipino TikTok creators, revealing education level as a key determinant of purchasing behavior. Extended TikTok engagement positively correlates with increased (...) purchasing likelihood. Filipino TikTok influencers significantly impact young professionals' purchasing decisions, emphasizing the need for tailored marketing strategies targeting this demographic. Recommendations were provided for effective influencer and digital marketing strategies targeting young professionals. (shrink)

Hacker communities of the 1970s and 1980s developed a quite characteristic work ethos. Its norms are explored and shown to be quite similar to those which Robert Merton suggested govern academic life: communism, universalism, disinterestedness, and organized scepticism. In the 1990s the Internet multiplied the scale of these communities, allowing them to create successful software programs like Linux and Apache. After renaming themselves the `open source software' movement, with an emphasis on software quality, they succeeded in gaining corporate interest. As (...) one of the main results, their `open' practices have entered industrial software production. The resulting clash of cultures, between the more academic CUDOS norms and their corporate counterparts, is discussed and assessed. In all, the article shows that software practices are a fascinating seedbed for the genesis of work ethics of various kinds, depending on their societal context. (shrink)

Two property regimes for software development may be distinguished. Within corporations, on the one hand, a Private Regime obtains which excludes all outsiders from access to a firm's software assets. It is shown how the protective instruments of secrecy and both copyright and patent have been strengthened considerably during the last two decades. On the other, a Public Regime among hackers may be distinguished, initiated by individuals, organizations or firms, in which source code is freely exchanged. It is argued that (...) copyright is put to novel use here: claiming their rights, authors write `open source licenses' that allow public usage of the code, while at the same time regulating the inclusion of users. A `regulated commons' is created. The analysis focuses successively on the most important open source licenses to emerge, the problem of possible incompatibility between them (especially as far as the dominant General Public License is concerned), and the fragmentation into several user communities that may result. (shrink)

This paper attempts to argue that a radically different notion of freedoms and rights that originates from the other, that is founded on the infinite responsibility for the other, and that demands an encounter with the other as pure alterity, could be a plausible starting point towards the conception and possible realization of a Levinasian society of neighbors. First, an explication is made on why a radical change in the area of freedoms and rights could be the starting point towards (...) a social, political, and moral philosophical framework based on the radical philosophy of Levinas as elaborated in his Otherwise than Being or Beyond Essence. Then, a discussion on conventional conceptions of freedoms and rights, particularly those based on liberalism, libertarianism, and utilitarianism, is presented as groundwork for a comparative analysis between these conventional conceptions and a radical notion that would be entailed by a conception of a Levinasian society of neighbors. Lastly, an attempt is made to characterize a radically different conception of freedoms and rights based on the philosophy of Levinas and to argue how it could be the starting point towards the conception and possible realization of a Levinasian society of neighbors. (shrink)

During the two last decades, speeded up by the development of the Internet, several types of commons have been opened up for intellectual resources. In this article their variety is being explored as to the kind of resources and the type of regulation involved. The open source software movement initiated the phenomenon, by creating a copyright-based commons of source code that can be labelled `dynamic': allowing both use and modification of resources. Additionally, such a commons may be either protected from (...) appropriation (by `copyleft' licensing), or unprotected. Around the year 2000, this approach was generalized by the Creative Commons initiative. In the process they added a `static' commons, in which only use of resources is allowed. This mould was applied to the sciences and the humanities in particular, and various Open Access initiatives unfolded. A final aspect of copyright-based commons is the distinction between active and passive commons: while the latter is only a site for obtaining resources, the former is also a site for production of new resources by communities of volunteers (`peer production'). Finally, several patent commons are discussed, which mainly aim at preventing patents blocking the further development of science. Throughout, attention is drawn to interrelationships between the various commons. (shrink)

How may human agents come to trust (sophisticated) artificial agents? At present, since the trust involved is non-normative, this would seem to be a slow process, depending on the outcomes of the transactions. Some more options may soon become available though. As debated in the literature, humans may meet (ro)bots as they are embedded in an institution. If they happen to trust the institution, they will also trust them to have tried out and tested the machines in their back corridors; (...) as a consequence, they approach the robots involved as being trustworthy (“zones of trust”). Properly speaking, users rely on the overall accountability of the institution. Besides this option we explore some novel ways for trust development: trust becomes normatively laden and thereby the mechanism of exclusive reliance on the normative force of trust (as-if trust) may come into play - the efficacy of which has already been proven for persons meeting face-to-face or over the Internet (virtual trust). For one thing, machines may evolve into moral machines, or machines skilled in the art of deception. While both developments might seem to facilitate proper trust and turn as-if trust into a feasible option, they are hardly to be taken seriously (while being science-fiction, immoral, or both). For another, the new trend in robotics is towards coactivity between human and machine operators in a team (away from making robots as autonomous as possible). Inside the team trust is a necessity for smooth operations. In support of this, humans in particular need to be able to develop and maintain accurate mental models of their machine counterparts. Nevertheless, the trust involved is bound to remain nonnormative. It is argued, though, that excellent opportunities exist to build relations of trust toward outside users who are pondering their reliance on the coactive team. The task of managing this trust has to be allotted to human operators of the team, who operate as linking pin between the outside world and the team. Since the robotic team has now been turned into an anthropomorphic team, users may well develop normative trust towards them; correspondingly, trusting the team in as-if fashion becomes feasible. (shrink)

Risk Management Strategies and Investment Behaviors are considered important factors in the investing activities of the retail investors. This study seeks to determine the relationship between Risk Management Strategies and Investment Behavior of Generation Z retail investors. The study is a correlational research and purposive sampling was used to select the respondents for this study. Cochran’s formula was utilized to determine the total sample size or total number of respondents. Spearman’s Rank-Order Correlation was employed to assess the significant relationship of (...) Risk Management Strategies and Investment Behaviors. Based on the results, it showed that risk management strategies have a significant relationship with one or more of the investment behaviors. Risk avoidance has a significant relationship with confirmation bias. Risk reduction has a significant relationship with all of the investment behaviors such as overconfidence, loss-aversion, recency bias, and confirmation bias. Risk transfer shows a significant relationship with only loss-aversion and confirmation bias. And lastly, risk acceptance also has a significant relationship with all of the investment behaviors. This study recommends exploring other types of behavioral biases under cognitive bias and emotional bias to determine their correlation with risk management strategies. Also, broadening the sample size, demographic scope, and geographic scope of the study can improve the generalizability of the study and provide a more comprehensive understanding of the relationship between investment behavior and risk management strategies. The researchers also recommend to utilize interviews and focus group discussions to gain an in-depth understanding of the underlying values and attitudes concerning investment behavior. (shrink)

The world of entrepreneurship has historically been linked with taking risks and the potential for significant rewards. However, there persists a notable gender imbalance in the entrepreneurial landscape, wherein women entrepreneurs remain a minority. Women navigating the entrepreneurial path encounter distinct challenges, setting their experiences apart from their male counterparts. In Balayan, Batangas, despite strides towards gender equality, women entrepreneurs continue to face challenges in the entrepreneurial landscape. This qualitative study delves into the experiences of 10 successful female entrepreneurs who (...) met specific criteria. Accordingly, semi-structured interviews are conducted, exploring various aspects of participants' experiences and revealing their motivations, achievements, challenges, and strategies. Thematic analysis reveals the connection between familial, community-driven, and personal motivations that drive these entrepreneurs forward. Despite facing obstacles such as financial constraints and gender biases, they prioritize financial gains and personal growth. With resilience, innovation, and dedication, these women overcome challenges and achieve success, utilizing support networks and online marketing strategies to their advantage. Recommendations include empowering women in entrepreneurship, strengthening support networks, introducing tailored financial literacy programs, and advocating against gender biases. Implement skill development initiatives and provide specialized education in online marketing. Engage in policy advocacy, celebrate success stories, and continuously research challenges and successes. Foster collaborative partnerships between businesses, educational institutions, and communities, and advocate for increased funding opportunities for sustainable growth. This research emphasizes the strength and capabilities of women entrepreneurs in Balayan, Batangas, affirming that "pink doesn't mean weak.". (shrink)

The results are interpreted in terms of a deficit in initial rule learning and subsequent generalization of these rules to new stimuli. Negative feedback is adequately processed at a neural level but this information is not used to improve behaviour on subsequent trials. As learning is degraded, the process of error detection at the moment of the actual response is diminished. Therefore, the current study demonstrates that disturbed error-monitoring processes play a central role in the often reported learning deficits in (...) individuals with PP. (shrink)

Comentario 3° en el marco de la tesis “Un Estudio en Metodología Intertextual y Exegética en Salmo 91” cuanto a mi trato, en aquel entonces, de las fuentes primarias (del testimonio documental) utilizadas asociadas a la referencia salmo 91:12 en favor de la fraseología מוט + רגל. Presentación del fragmento 5 del plato 1032 (b-366315) como siendo la confirmación de la existencia de testimonio documental para la variante conjetural propuesta por mí en la tesis (en el capítulo 4) referente a (...) la tradición observada en salmo 91:12. . . Autor: Anderson Rodrigues de Paula (RG brasileiro MG-15.713.736 y DNI argentino: 95.036.821). Fecha y lugar de la primera aparición del presente comentario: 3/1/2023, en el perfil de Academiaedu del propio autor del comentario (rosario . academia. edu/AndersonRodriguesdePaula). Aunque desde el 31/12/2022, a causa de lo que expongo a continuación, instituciones y revisores han tenido contacto privado con los hallazgos que exhibo en el presente comentario. . . Observación: lo que posibilitó el presente análisis fue la generosidad de Israel Antiquities Authority (IAA) en permitirme tener acceso a imágenes de determinados manuscritos en condiciones no disponibles en The Leon Levy Dead Sea Scrolls Digital Library. En este preciso momento mientras escribo el presente comentario me encuentro ya en el proceso de trámite para obtener el permiso de uso de imágenes y así poder insertarlas en un artículo el cual ya está listo el cual pretendo publicar en el cual expongo con más detalles y gráficamente (mediante las imágenes de los manuscritos) todo el análisis que describo a continuación. (shrink)

Successful teamwork doesn't work overnight, what makes teamwork potent is team building. (Plagiarism) According to Abdullah, et. al., (2022) team building training can improve group cohesiveness or the quality of sticking together or unity teamwork more likely to be higher with a significant score difference. This study used mixed methods both qualitative and quantitative data collection, and an analysis method to answer the research method, random sampling is named as such because the data set is chosen via random selection, where (...) every member of the population has an equal probability of being selected (Tao, 2023). The respondents were 100 restaurant employees and 10 managers from the chosen restaurant in Malolos City in Bulacan. The subcategories of team building, including activities, communication, skills, personality, problem-solving, and values, have all received a consensus of strong agreement, with weighted averages falling within the range of 3.26 to 3.44. This level of agreement aligns with the scores for motivation at 3.43 and productivity at 3.38. These values have been calculated by determining the mean, which spans from 3.25 to 4.00. The advantages of team building that is being observed by the managers is to create familiarity and teamwork among the employees, to improve the quality of service and the quality of the food especially the respondents are in the food service sector, development, and training for the employees to achieve the establishments’ goal and lastly rebuilding and build a relationship with one employee to another. However, for the disadvantages, it costs a lot of money to conduct team building in the management. Therefore, the null hypothesis is rejected. Despite the fact that there is a low correlation between teambuilding activities and motivation and employee productivity, there is still a significant relationship between the variables. (shrink)

This paper introduces the Las Piñas Bamboo Organ as a cultural treasure. By interviewing four key individuals related to the bamboo organ, the paper discusses the history, present condition, and activities related to the preservation and sustenance of the bamboo organ. Interview, a method of oral history, was chosen to let the people involved share their own memories and experiences that are not usually featured in written documents about the bamboo organ. The following themes emerged from the interviews: (1) the (...) introduction of Father Diego Cera as an organ builder, (2) the motivations in using bamboo as the main material of the bamboo organ, (3) the quality of the sound produced by the bamboo organ, (4) the restoration of the bamboo organ, (5) the beginnings, objectives, and activities of the Bamboo Organ Foundation, Inc., (6) the beginnings and objectives of the International Bamboo Organ Festival and the activities related to it, (7) the problems that the bamboo organ faces, and (8) the importance of training organists. The researchers also identified the implications of the conservation of the bamboo organ in the economic, social, ecological, and cultural aspects of the city’s social life based on its potentials for development. This paper can be a useful primary source for future researchers of the bamboo organ and the local history of Las Piñas. (shrink)

A carne bovina é uma das proteínas mais consumidas no mundo, favorecendo o comércio exterior. O Brasil é um dos grandes exportadores desse produto, o que leva à importância de buscar meios para se obter maior eficiência reprodutiva e produtiva. Dentre esses métodos, o uso de Inseminação Artificial em Tempo Fixo (IATF) vem aumentando e com isso vem a busca por estratégias para alcançar melhores taxas de prenhez. Uma estratégia é avaliar a nutrição do animal em conjunto com a condição (...) corporal. Assim a proposta desse trabalho é verificar a influência do Escore de Condição Corporal (ECC) na taxa de prenhez em vacas Nelore submetidas à IATF. O estudo foi realizado em propriedade particular no município de Cacoal, Rondônia, com 150 vacas da raça Nelore, multíparas, com idade média de 5 anos, submetidas ao manejo de pastejo semi-intensivo. Foram separados dois grupos sendo, grupo A: 75 vacas com escore ≥ 3,0 e grupo B: 75 matrizes com escore ≤2,5. Ambos passaram pelo mesmo protocolo farmacológico, dividido em três etapas (D0, D8 e D10). A inseminação artificial foi realizada no D10 e após 30 dias as vacas dos dois grupos passaram pelo diagnóstico de gestação, por ultrassonografia. Os resultados demonstraram que a taxa de prenhez do grupo A (68%) foi maior que a do grupo B (40%), sendo relevante a preocupação com o ECC de vacas Nelore em protocolos de IATF. (shrink)

Review of Jan van der Stoep's published PhD dissertation on the work of Pierre Bourdieu.en de politieke filosofie van het multiculturalisme Kok Kampen 2005. My review is in English. van der Stoep's book is in Dutch with an English summary.

BĪRŪNĪ, ABŪ RAYḤĀN MOḤAMMAD b. Aḥmad (362/973- after 442/1050), scholar and polymath of the period of the late Samanids and early Ghaznavids and one of the two greatest intellectual figures of his time in the eastern lands of the Muslim world, the other being Ebn Sīnā.

Epitome L'Univers Les plus loin scintillements de l'Univers ne sont pas une lointaine bordure de finition. Mais des voyageurs concernés, émissaires de l’âge lumière. Ainsi, ici et dans le présent, dans un moment, au-delà dans l'obscurité, se dévoile l'assise du passé energetique, de l’âge noir de l'Univers. Martin J. B. Thibault Janvier 2021 .

Fizik disiplininde astronomiye yönelik sorular Johannes Kepler (1571-1630) ve Isaac Newton (1643-1727) gibi fizik alanında devrim yaratan düşüncelerin ortaya çıkmasına yol açmıştır. Kepler ‘Yeni Astronomi’ (Astronomia Nova), ‘Dünya'nın Uyumu’ (Harmonice Mundi) ve ‘Kopernik Astronomisinin Özeti’ (Epitome Astronomiae Copernicanae) adlı çalışmalarından hareketle ileri sürdüğü gezegensel hareket yasaları, Newton ise 1687 yılında yayımlanan ‘Doğa Felsefesinin Matematiksel İlkeleri’ (Philosophiae Naturalis Principia Mathematica) isimli çalışmasında yer verdiği hareket yasaları ile fizik disiplininde Aristoteles fiziğinin terk edilerek yeni bir fizik anlayışının ortaya çıkmasına ve böylece fizik (...) alanında bir devrimin meydana gelmesine sebep olmuşlardır. Fizik disiplininde gerçekleşen bu devrimin bir benzeri ise canlıların çalışılması ya da biyoloji disiplini söz konusu olduğunda 1800’lerden biraz daha geç bir zamana rastlamaktadır. Biyolojide gerçekleşen devrimsel düşünce doğal seçilim mekanizması ile canlılarda zaman içerisinde gerçekleşen değişim ve dönüşüm sürecini açıklayan Charles Darwin’in evrim kuramına yönelik görüşlerini ortaya koymasına tekabül etmektedir. Bu kapsamda çalışmada öncelikli olarak canlılarda meydana gelen değişim süreçlerine yönelik tespitleri ile Darwin’in görüşlerinin olgunlaşmasına katkıda bulunan Fransız Transformistler (Dönüşümcüler) olarak da bilinen Georges-Louis Leclerc (Comte de Buffon), Jean-Baptiste Lamarck ve George Cuvier’in görüşlerine yer verilmektedir. Ardından bu bilim insanlarının canlılardaki dönüşümsel ya da evrimsel değişime ilişkin argümanlarının Darwin’in evrim kuramını nasıl etkilediği ve bu etkilerin sonucunda biyoloji biliminde nasıl bir devrimin ortaya çıkmasına yardımcı oldukları aktarılmakta ve bu çerçevede Darwin’in on dokuzuncu yüzyılda biyoloji biliminde devrime yol açan tespitlerine ve evrim kuramının ayrıntılarına yer verilmektedir. (shrink)

Resumo A transferência de embriões em bovinos tem o objetivo principal de aprimorar o melhoramento genético e otimizar a reprodução bovina A importância dessa prática é destacada pela sua contribuição para a maximização de características desejadas nos rebanhos, como qualidade de carne, eficiência reprodutiva e resistência a condições ambientais adversas. Este trabalho descreve e analisa as técnicas avançadas utilizadas nesse processo, incluindo seleção genômica, sexagem de embriões, produção in vitro, protocolos não cirúrgicos, sincronização reprodutiva, criopreservação de embriões e uso de (...) marcadores de fertilidade. A compreensão aprofundada dessas técnicas é fundamental para o sucesso da transferência de embriões, bem como para a capacidade de personalizar e aprimorar as características específicas dos rebanhos. Enfatizando a importância da expertise de profissionais especializados em reprodução bovina, este trabalho busca oferecer uma visão abrangente das práticas atuais e avanços tecnológicos nesse campo. Ao unir ciência e prática, torna-se importante a comparação de técnicas, bem como relacionar resultados eficientes para promover qualidade genética, trazer a sustentabilidade e envolver a técnica em um cenário atualizado da indústria. Palavras-chave: Embriões; Hormônio; Reprodutor. -/- Abstract Embryo transfer into cattle has the main objective of improving genetic improvement and optimizing bovine reproduction. The importance of this practice is highlighted by its contribution to maximizing desired characteristics in herds, such as meat quality, reproductive efficiency and resistance to environmental conditions adverse. This work describes and analyzes the advanced techniques used in this process, including genomic selection, embryo sexing, in vitro production, non-surgical protocols, reproductive synchronization, embryo cryopreservation and the use of fertility markers. An in-depth understanding of these techniques is critical to the success of embryo transfer, as well as the ability to customize and enhance specific herd characteristics. Emphasizing the importance of the expertise of professionals specialized in bovine reproduction, this work seeks to offer a comprehensive view of current practices and technological advances in this field. When combining science and practice, it becomes important to compare techniques, as well as relate efficient results to promote genetic quality, bring sustainability and involve the technique in an updated industry scenario. Keywords: Embryos; Hormone; Reproducer. -/- REFERÊNCIAS BIBLIOGRÁFICAS ABIEC. Associação Brasileira das Indústrias Exportadoras de Carnes. Beef Report. Perfil da Pecuária no Brasil. v.6, p. 7, 2021. ALVAREZ, R. Transfer of blastocysts derived short-term in culture of quality morulae in vivo. Domestic Animals. v.9, p. 790, 2007. ALVES, N. G. Atividade Ovariana em Fêmeas Bovinas da Raça Holandesa e Mestiças Holandês x Zebu, Durante Dois Ciclos Estrais Normais Consecutivos. Revista Zootecnia. v.7, p. 86, 2002. ANDRADE, J. Use of hormone treatments to superovulation Nelore donors. Reproduction Science. v.9, p. 70, 2002. Associação Brasileira de Inseminação Artificial (ASBIA). Index Asbia 2021. v.7, p. 6, 2021. Associação Brasileira de Inseminação Artificial (ASBIA). Index ASBIA Mercado, v.8, p. 6, 2019. BARROS, C. M. Tratamentos superestimulatórios utilizados em protocolos para a transferência de embriões bovinos. Acta Scientiae Veterinariae. v.9, p.8, 2007. BARUSELLI, P. S. Avaliação do mercado de IATF no Brasil. Boletim Eletrônico do Departamento de Reprodução Animal – FMVZ/USP, 1. ed., v.8, p.7, 2019. BARUSELLI, P. S.; CATUSSI, B. L. C.; ABREU, L. A.; ELLIFF, F. M.; SILVA, L. G.; BATISTA, E. S.; CREPALDI, G. A. Evolução e perspectivas da Inseminação Artificial em bovinos. Revista Brasileira de Reprodução Animal, v.43, n.2, p.308-314, 2019. 13 BARUSELLI, P. S. IATF gera ganhos que superam R$ 3,5 bilhões nas cadeias de produção de carne e de leite. Boletim Eletrônico do Departamento de Reprodução Animal/FMVZ/USP, 2.ed., v.8, n.8, p.7, 2019. BINELLI, M. Anti-luteolytic to improve in cattle. Acta Scientiae Veterinariae. v.9, p.8, 2001. BÓ, G. A. Manipulação hormonal do ciclo estral em doadoras e receptoras de embrião bovino. Acta Scientiae Veterinariae. v.9, p.7, 2004. BÓ, G.; MAPLETOFT, R. Evaluation and of bovine. Animal Reproduction. v.8, p.9, 2013. BUSS, V. Efeito da dose e momento da administração de eCG em protocolos de IATF aplicados e vacas de corte em anestro. Universidade Federal do Pampa, Dissertação – Programa de Pós-Graduação em Ciência Animal, v.8, n.8, p.9, 2020. Centro de Estudos Avançados em Economia Aplicada (CEPEA). Boletim do leite. São Paulo, Ano 25, n.286, 2019. CHAVES, D. F.; ALVES, M. J. Protocolo de receptoras de embriões: índices de aproveitamento de corpo lúteo e taxa de prenhez. Animal Reproduction. v.9, p.7, 2023. DA SILVA, Emanuel Isaque Cordeiro. Fisiologia Clínica do Ciclo Estral de Vacas Leiteiras: Desenvolvimento Folicular, Corpo Lúteo e Etapas do Estro. 2020. DA SILVA, Emanuel Isaque Cordeiro. Transferência de Embriões nos Animais e a Indústria de Embriões no Brasil. 2020. DALCIN, L.; LUCCI, C. M. Criopreservação de embriões de animais de produção: princípios criobiológicos e estado atual. Rev. Bras. Reprod. Anim. v.7, p.7, 2010. DANTAS, K. S. A. Seleção de receptoras em um programa de transferência de embriões (PIVE) em bovinos no nordeste do Brasil. Ciência Animal. v.9, p.7, 2018. D’AVILA, C. A.; MORAES, F. P.; LUCIA J. R. T.; GASPERIN, B. G. Hormônios utilizados na indução da ovulação em bovinos – Artigo de revisão. Revista Brasileira de Reprodução Animal, v.43, n.4, p.797-802, 2019. DEMÉTRIO, D. G. B. Colheita e transferência de embriões bovinos. Dissertação (Mestrado em Reprodução Animal) – Faculdade de Medicina Veterinária e Zootecnia da UNESP, Campus de Botucatu, São Paulo. v.9, p.76, 2003. FAO – Organização das Nações Unidas para a Alimentação e Agricultura. O Estado da Insegurança Alimentar e Nutrição no Mundo (SOFI) 2021. Faculdade de Medicina Veterinária e Zootecnia da UNESP. v.4, n.6, p.6, 2021. FILHO, L. C. C. Fatores que interferem na eficiência reprodutiva de receptoras de embrião bovino. Arq. Ciênc. Vet. Zool. v.7, p.9, 2013. GONZÁLEZ, F. H. D. Introdução a Endocrinologia Reprodutiva Veterinária. UFRGS. v.9, p.7, 2002. GOODHAND, K. In vivo recovery and vitro embryo from bovine aspirated at frequencies or FSH treatment. Animal Reproduction. v.8, p.87, 1999. 14 HAFEZ, E. S. E.; HAFEZ, B. Reprodução animal. 7ed. Barueri: Manole. v.7, p.7, 2004. HONORATO, M.T. Importância da escolha de receptoras em um programa de transferência de embriões em bovinos. Barueri: Manole. v.8, p.6, 2013. HOPPER, R. Bovine Reproduction. Blackwell. v.8, p.8, 2015. IBGE. Instituto Brasileiro de Geografia e Estatística. Pesquisa da Pecuária Municipal 2021 (PPM 2021). IBGE. v.9, n.7, p.7, 2021. KONIG, H. E.; LIEBICH, H. G. Anatomia dos animais domésticos: texto e atlas colorido. Vol.2. Porto Alegre: Artmed, v.2, p.4, 2004. MARTINS, F. S. Fatores reguladores da foliculogênese em mamíferos. Rev Bras Reprod Anim. v.3, p.9, 2008. MELLO, R. R. C. Desenvolvimento folicular inicial em bovinos. Rev. Bras. Reprod. Anim. v.8, p.9, 2013. OLIVEIRA, A. F. M. Principais hormônios que controlam o comportamento reprodutivo e social das fêmeas ruminantes – Revisão. Rev. Bras. Reprod. v.9, p.8, 2014. OLIVEIRA, C. S. Biotécnicas da Reprodução em Bovinos. EMBRAPA, v.8, p.8, 2014. PASA, C. Transferência de embriões em bovinos. Biodiversidade. v.9, p.9, 2008. PENITENTE FILHO, J. M. Produção de embriões bovinos in vivo e in vitro. Revista CFMV, Ano XX. v.8, p.8, 2014. PHILLIPS, P. E.; JAHNKE, M. M. Embryo Transfer (Techniques, Dono rs, and Recipients). Vet Clin Food Anim, v.9, p.8, 2016. RODRIGUES, J.; BERTOLINI, M. Biotecnologias da reprodução animal: de Aristóteles à edição gênica. Rev. Bras. Reprod. Anim. v.8, p.7, 2019. SANTOS, K. J. G. Biotecnologias reprodutivas e fisiologia reprodutiva da fêmea bovina – conhecimento para o sucesso. Rev. Bras. Reprod. Anim. v.8, p.98. 2012. SANTOS, P. H. Impactos da superestimulação ovariana sobre a diferenciação das células da granulosa bovina. Dissertação de Mestrado em Farmacologia e Biotecnologia – UNESP, v.8, p.8. 2017. SILVA, P. R. B. Regulação farmacológica do ciclo estral de bovinos. UNESP. v.9, p.8. 2011. (shrink)

Foucault's governmentality lectures at the Collège de France analyze the history of the state through the lens of governmental reason. However, these lectures largely omit consideration of the relationship between discipline and the state, prioritizing instead raison d'État and liberalism as dominant state technologies. To remedy this omission, I turn to Foucault's early studies of discipline and argue that they provide materials for the reconstruction of a genealogy of the "disciplinary state." In reconstructing this genealogy, I demonstrate that the disciplinary (...) state marks the "dark side" of the liberal state, a dark side which is, moreover, largely obscured in the governmentality lectures. I further construe the difference between this early genealogy of the state and the later governmental studies in methodological terms. At stake in this difference is the historiographic status of capitalism and social conflict. Foucault's governmentality lectures employ what I term an "idealist disavowal," thereby treating capitalism and social conflict as irrelevant to the history of the state. The early disciplinary studies, on the other hand, enact a "materialist avowal," by which these objects are avowed as central to the explanation of how and why the state develops. Finally, I argue that Foucault's governmental genealogy of the liberal state is explanatorily and analytically incomplete, while the genealogy of the disciplinary state contributes to its completion on both fronts. (shrink)

This article reconstructs and defends Theodor Adorno’s social theory by motivating the central role of abstract domination within it. Whereas critics such as Axel Honneth have charged Adorno with adhering to a reductive model of personal domination, I argue that the latter rather understands domination as a structural and de-individualized feature of capitalist society. If Adorno’s social theory is to be explanatory, however, it must account for the source of the abstractions that dominate modern individuals and, in particular, that of (...) value. While such an account remains undeveloped in Adorno, Marx provides resources for its development, in positing the constitution of value neither in production nor exchange alone, but in the social totality. This article argues that Marx’s account is compatible with Adorno’s, and that it may be used to render Adorno’s theory of domination more credible on explanatory grounds. (shrink)

Through an analysis of a part of Thomas’ arguments on the rational soul’s subsistence, the article exposes the reasons why it is necessary and possible to affirm that the human soul is a substance in its proper sense, even if it does not have the entire human essence when it subsists apart from the body. Thus the article intends to answer a question raised by B.C. Bazán. The analysis is articulated applying the principle nihil agit nisi secundum quod est actu (...) in different ways in order to make explicit the reason why the soul is the suppositum of intellectual operations and faculties and therefore a substance; then the article reaffirms that the substantial form’s definition is related to the act of being in order to distinguish the “virtual” way in which any substantial form has the entire species, from the “real” way in which any substance has an entire substantial essence. (shrink)

The article analyzes the a posteriori argumentation for the existence of God present in saint Anselm’s Monologion. It defends that the arguments in chapters I-IV are parts of a single argumentative way comparable with the fourth way of Thomas Aquinas. The only starting point for the argumentation is the evidence of the degrees of transcendental perfection (goodness and greatness) found in things. According to this single point of departure, the argument also has a single formulation of the principle of causality (...) given in chapter I. By this principle, Anselm infers the existence of a single first principle (that which is through itself) from its effects (that which is through another). Contrary to what is usually held, it is shown that chapters III and IV do not contain arguments properly meant to demonstrate God’s existence. Chapter III’s specific goal is to demonstrate the impossibility that that which is through itself may be something multiple, while chapter IV aims to demonstrate the impossibility that the supreme nature through whom all things exist may be overcome or equaled in dignity by another. Both arguments depend of the principle of causality formulated in chapter I to be conclusive. (shrink)

An hommage of Yvanka B. Raynova to Ana-Teresa Tymieniecka, including personal mementoes, and an overview of her philosophical work, editorial activities, and conferences within the World Institute of Phenomenology.

"Gok kubbede kalan ancak hos seda'dir" deyimi dogrudur. "Su ustune yazi yazmaya" esittir. Dusunceleri bekletmeden duzenli olarak kayitlamak geregi, surekli okumak; okunanlari anlamak ve anlatmak aliskanligi kadar onemlidir. Neresinden bakilirsa bakilsin, deney ve dusunce yolu ile birikmis bilgiler kagida aktarilmaz, basilip yayinlanmaz ise, eninde sonunda kaybolup gider. "Yeni Dunya'yi yeniden kesfetmek" gibi, yeni bastan degisik kisilerce durmadan "yaratilmalari" gerekir. Bu da, bir toplum icin, cok yuksek giderli bir kayiptan baska birsey degildir. Bu gorus'un incelenmesi, bu kitabin icindeki bildirilerde ele alinmaktadir. (...) Sozu edilen bildiriler 1982 ile 1992 yillari arasinda kagida dokulmus, bir bolumu de bu sure icinde Asya, Avrupa ve Amerika'da yayinlanmakta olan degisik dergilerde yer almistir. Daha once basilmis bildiriler, birbirlerini tamamlayici olmalari bakimindan ve icinde yayinlandiklari dergi ve kitaplarin tumunun her kitaplikta bulunmayabilecegi de goz onunde tutularak, bugun'e dek basilmamis olanlarla biraraya getirilmistir. (shrink)

What sort of moral theory should we view Saint Anselm of Canterbury as holding and using in his writings? In this paper, I argue that Anselm is best understood as a virtue ethicist. In the first part of the paper, I consider whether his approach could be understood in terms of deontological or natural law theories. In the second, I make a case for Anselm being a virtue ethicist. In the third part, I focus on this theme as found in (...) treatises published during Anselm’s lifetime. In the fourth, I look at other texts within the Anselmian corpus, notably the De humanibus moribus and the Dicta Anselmi. In the fifth and sixth parts, I turn to Anselm’s letters, focusing first on general discussions, and then on discussions focused upon specific virtues and vices. -/- . (shrink)

RESUMO A alimentação é o fator que mais onera um sistema de produção animal. Assim, a utilização de diferentes estratégias de alimentação dos animais ainda é o grande desafio da nutrição animal, principalmente, levando em consideração as exigências nutricionais de diferentes categorias de ruminantes, em especial bovinos em regiões tropicais, haja vista que a sazonalidade na produção de forragens afeta diretamente a produção bovina, promovendo inadequação no atendimento das exigências nutricionais dos animais principalmente em minerais e vitaminas. Uma alimentação que (...) não atenda as exigências nutricionais dos ruminantes gera prejuízos no sistema de produção, além de, em casos mais graves, ocasionar a perda do animal. Estudos que abordam o efeito e a importância de vitaminas e minerais na nutrição bovina são escassos e necessários. Recentemente a National Research Council (NRC) apresentou novos registros das exigências nutricionais das vitaminas e minerais. Essas alterações proporcionam um impacto econômico significativo em relação à nutrição animal. Nesse sentido, objetivou-se com esta revisão trazer informações acerca de vitaminas e minerais na nutrição de bovinos em pastejo. -/- Palavras-chave: Alimentação animal; forragem; pastagem; requerimentos nutricionais; ruminantes; vitaminas lipossolúveis (Source: AGROVOC). -/- ABSTRACT Animal feed is the factor that most burdens a production system. Thus, the use of different animal feeding strategies is still the great challenge of animal nutrition, taking into account the nutritional requirements of different categories of ruminants, especially cattle in tropical regions, given that seasonality in forage production directly affects cattle production, promoting inadequacy in meeting the nutritional requirements of animals, mainly in minerals and vitamins. A diet that does not meet the nutritional requirements of ruminants generates losses in the production system, in addition to, in more serious cases, causing the loss of the animal. Studies that address the effect and importance of vitamins and minerals in bovine nutrition are scarce and necessary. Recently the National Research Council (NRC) presented new records of the nutritional requirements of vitamins and minerals. These changes provide a significant economic impact on animal nutrition. In this sense, the objective of this review was to bring information about vitamins and minerals in the nutrition of grazing cattle. -/- Keywords: Animal feeding; fat soluble vitamins; forage; nutritional requirements; pasture feeding; ruminants (Source: AGROVOC). -/- REFERÊNCIAS BIBLIOGRÁFICAS -/- 1. Cavalcanti CPL, Silva e Macedo TJ, Gois GC, Menezes VG, Monte APO, Silva AD, Silva DJM, Silva EO, Araújo GGL, Rodrigues RTS, Wischral A, Matos MHT, Queiroz MAA. 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French translation by G. B. Côté and Roger Lapalme of "A Geneticist's Roadmap to Sanity" (G. B. Côté, 2019) with added bibliography. -/- À voir le monde d’aujourd’hui, on pourrait croire que nous avons perdu la raison. Je veux explorer ici les fondements mêmes de notre existence. Je discuterai brièvement du libre arbitre, de l’éthique, de la religion, de la souffrance, du dualisme cartésien et de l’état de conscience, avec un arrière-plan promulguant l’importance de la physique quantique d’aujourd’hui et de (...) l’intemporel. Pour ce faire, je devrai d’abord établir que le platonisme mathématique est une prémisse essentielle pour qu’un univers (ou même un multivers) prenne forme, et j’introduirai les trois modes d’existence abstrait, virtuel et concret (en philosophie) correspondant respectivement aux concepts d’information, d’énergie et de masse (en physique). Cet article constitue un bref exposé de ma théorie du tout. (shrink)

Philosophers of science commonly connect ontology and science, stating that these disciplines maintain a two-way relationship: on the one hand, we can extract ontology from scientific theories; on the other hand, ontology provides the realistic content of our scientific theories. In this article, we will critically examine the process of naturalizing ontology, i.e., confining the work of ontologists merely to the task of pointing out which entities certain theories commit themselves to. We will use non-relativistic quantum mechanics as a case (...) study. We begin by distinguishing two roles for ontology: the first would be characterized by cataloging existing entities according to quantum mechanics; the second would be characterized by establishing more general ontological categories in which existing entities must be classified. We argue that only the first step is available for a naturalistic approach; the second step not being open for determination or anchoring in science. Finally, we also argue that metaphysics is still a step beyond ontology, not contained in either of the two tasks of ontology, being thus even farther from science. (shrink)

How to account for the power that art holds over us? Why do artworks touch us deeply, consoling, transforming or invigorating us in the process? In this paper, we argue that an answer to this question might emerge from a fecund framework in cognitive science known as predictive processing (a.k.a. active inference). We unpack how this approach connects sense-making and aesthetic experiences through the idea of an ‘epistemic arc’, consisting of three parts (curiosity, epistemic action and aha experiences), which we (...) cast as aspects of active inference. We then show how epistemic arcs are built and sustained by artworks to provide us with those satisfying experiences that we tend to call ‘aesthetic’. Next, we defuse two key objections to this approach; namely, that it places undue emphasis on the cognitive component of our aesthetic encounters—at the expense of affective aspects—and on closure and uncertainty minimization (order)—at the expense of openness and lingering uncertainty (change). We show that the approach offers crucial resources to account for the open-ended, free and playful behaviour inherent in aesthetic experiences. The upshot is a promising but deflationary approach, both philosophically informed and psychologically sound, that opens new empirical avenues for understanding our aesthetic encounters. -/- This article is part of the theme issue ‘Art, aesthetics and predictive processing: theoretical and empirical perspectives’. (shrink)

Como aparece a pornografia como um discurso e saber sobre o corpo? Qual é a relação que existe entre pornografia e a produção de subjetividade? Como funciona a pornografia dentro dos mecanismos políticos de normalização do corpo e da visão na cidade moderna? Essa pesquisa muito rápida se trata de realizar uma análise dos primeiros apontamentos realizados em Testo Yonqui (2008) e que antecedem ao Pornotopía (2010), em que em um primeiro momento se faz a proposta de uma releitura dos (...) termos presentes no debate pornográfico (sujeito, olhar, representação, prazer...), assim como das suas relações com a história da arte e as suas estratégias biopolíticas de controle do corpo e de produção de prazer através do olhar. Em um segundo momento, tenta-se aqui mostrar como e por qual razão a pornografia é uma forma de produção cultural que concerne ao museu, em como o museu produz uma categoria de lixo urbano a partir da pornografia como um amplo dispositivo biopolítico de controle e privatização da sexualidade na cidade moderna e, ao fim, por qual razão a pornografia se converteu a partir dos anos setenta em um espaço de análise, en uma ferramenta crítica e de reapropriação para as micropolíticas de gênero, sexo, raça e sexualidade. (shrink)

Una visión de la película de Lars Von Trier: Anticristo.

English title: "The early literary education of the young José Gaos in Valencia (1915-1919)"Resumen: Nuestra intención en este texto es investigar acerca de los primeros años de formación del pensamiento de José Gaos (1900-1969); así pues, no parece ser demasiado erróneo pensar que aquél, hacia 1915 no era, aún, puramente “filosófico”: la Filosofía representaba parte de su formación, cumpliendo el mismo papel —eso sí: básico y fundamental— que desempeñó la Literatura. El primer auténtico encuentro con la Filosofía se daría antes (...) de su llegada a Valencia, en ese mismo año de 1915; pero ese también es el año en que Gaos recibirá una sólida formación estético-literaria a través de prensa y revistas filosóficas, especialmente en el grupo que conformó junto con Max Aub, José Medina Echeverría y su hermano Carlos Gaos. Abstract: This paper investigates in detail about the early years of José Gaos (1900-1969) and his education in philosophy and literature. Therefore, we know that their studies (academic or not) were not purely “philosophical” in 1915. Literature and philosophy played in Gaos an equally important role. The first real encounter with philosophy happens before he comes to Valencia in 1915; but in this year Gaos also receives a strong education, in aesthetic and literary, through press and philosophical journals, and especially within the group formed with Max Aub, José Medina Echeverría and his brother Carlos Gaos. Palabras clave: José Gaos, literatura, juventud, formación, Valencia. Keywords: José Gaos, literature, youth, education, Valencia. (shrink)

A “self-effacing” property is one that is definable without referring to it. Colin McGinn (2000) has argued that there is exactly one such property: truth. I show that if truth is a self-effacing property, then there are very many others—too many even to constitute a set.

Entre as alternativas investigadas para suprir o déficit de órgãos disponíveis para transplante está o uso de animais não-humanos como fornecedores de órgãos, técnica conhecida como xenotransplante. Embora os primeiros experimentos desse tipo remontem a mais de um século, e as pesquisas tenham progredido nas últimas décadas impulsionadas pelos avanços em manipulação genética, o procedimento ainda permanece desconhecido para grande parte da população, com escassa discussão acerca de seus desafios e implicações éticas. Desta forma, este estudo tem uma dupla finalidade: (...) (a) consolidar dados relevantes que evidenciam a complexidade que transcende a execução clínica do procedimento, proporcionando elementos para uma análise ética da xenotransplantação, e (b) fomentar a reflexão crítica e encorajar outras pessoas a se engajarem em uma discussão rigorosa e detalhada sobre o assunto. Refletindo esta preocupação, o trabalho foi estruturado em duas seções. A primeira seção, de caráter descritivo, reúne informações técnico-científicas. O Capítulo 1 debruça-se sobre as complexidades, desafios e limitações do sistema tradicional de transplantes. Já no Capítulo 2 é traçado um panorama histórico da xenotransplantação, priorizando o xenotransplante de órgãos. A segunda seção apresenta os dilemas éticos advindos da xenotransplantação. No Capítulo 3 abordo o equilíbrio entre os (possíveis) direitos individuais dos pacientes a receberem órgãos de origem animal e os riscos coletivos associados às xenozoonoses; preocupações relativas ao monitoramento e potencial invasão de privacidade dos pacientes xenotransplantados e seus entes próximos; desafios e limitações no processo de consentimento livre e informado dos pacientes; a postura do sistema de saúde face aos pacientes que declinarem de órgãos de origem animal ou que optarem pelo xenotransplante; os recentes casos de uso de pacientes com morte encefálica em experimentos de xenotransplantação de órgãos e suas possíveis repercussões; e, por fim, nos dedicamos à reflexão sobre a utilização de animais não-humanos, com foco nas justificativas que buscam legitimar este uso. Os capítulos foram estruturados de modo que, juntos, estabeleçam uma narrativa contínua, em que a análise de conceitos, argumentos e preocupações em um capítulo conduzem ao tema subsequente. Ao término, espero que delineiem um panorama abrangente das questões envolvidas, e forneçam uma argumentação fundamentada e coerente que respalde a conclusão de que a prática de xenotransplantação de órgãos deve ser abandonada e avaliada como moralmente errada. (shrink)

Deep Brain Stimulation (DBS) is a relatively new, experimental treatment for patients suffering from treatment-refractory Obsessive Compulsive Disorder (OCD). The effects of treatment are typically assessed with psychopathological scales that measure the amount of symptoms. However, clinical experience indicates that the effects of DBS are not limited to symptoms only: patients for instance report changes in perception, feeling stronger and more confident, and doing things unreflectively. Our aim is to get a better overview of the whole variety of changes that (...) OCD patients experience during DBS treatment. For that purpose we conducted in-depth, semi-structured interviews with 18 OCD patients. In this paper, we present the results from this qualitative study.We list the changes grouped in four domains: with regard to (a) person, (b) (social) world, (c)characteristics of person-world interactions, and (d) existential stance. We subsequently provide an interpretation of these results. In particular, we suggest that many of these changes can be seen as different expressions of the same process; namely that the experience of anxiety and tension gives way to an increased basic trust and increased reliance on one’s abilities. We then discuss the clinical implications of our findings, especially with regard to properly informing patients of what they can expect from treatment, the usefulness of including CBT in treatment, and the limitations of current measures of treatment success. We end by making several concrete suggestions for further research. (shrink)

Herder’s earliest philosophical writing, the essay fragment Versuch über das Sein, explores the concept of Being (Sein) in dialogue with Kant’s pre-critical Der einzig mögliche Beweisgrund zu einer Demonstration des Daseins Gottes. In this often critically omitted work, Herder arrives at a number of insights that would be determinative for the development of his later thought. This examination details Herder’s concept of Being as the transcendent ground of predication, his contention that Being can never be experienced directly, and his consequent (...) conclusion that the shape of philosophical inquiry should not be one of abstract speculation, but instead one of non-foundational, historically aware, empirical observation. This consideration then briefly addresses how the concept of Being informs Herder’s philosophy of science, history, language and religion. (shrink)

My aim is to show that, in Posterior Analytics B 8, the conception of lunar eclipse brought about by pre-demonstrative knowledge (hoti) is deeply vague and radically different from the one obtained by demonstrative knowledge (dioti).

We examine the discussion about the definition of knowledge as true judgment accompanied by logos in Theaetetus 201c-210c, in order to ascertain which of the recent alternative interpretations is more consistent with the text. To accomplish this, we intend to analyze the text and explore in detail the secondary literature about it.

Here you can download Torrijos' contribution to this book: the general Presentation and the Introduction to the second part.